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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5J
All Species:
16.36
Human Site:
S580
Identified Species:
40
UniProt:
Q15735
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15735
NP_001002837.1
1006
107197
S580
D
N
F
Q
T
I
L
S
L
Q
Q
F
Q
G
P
Chimpanzee
Pan troglodytes
A0FI79
644
70203
S270
I
R
S
K
D
V
R
S
R
S
Y
L
E
G
S
Rhesus Macaque
Macaca mulatta
XP_001110784
811
87406
D437
L
H
Q
L
W
E
K
D
Q
L
N
M
A
K
N
Dog
Lupus familis
XP_543486
1008
107177
S582
D
N
F
Q
T
I
L
S
L
Q
Q
F
P
G
P
Cat
Felis silvestris
Mouse
Mus musculus
P59644
1003
107585
S577
D
N
F
Q
T
I
L
S
L
Q
Q
F
Q
G
P
Rat
Rattus norvegicus
Q9JMC1
1001
107190
S575
D
N
F
Q
T
I
L
S
L
Q
Q
F
Q
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507443
768
84124
L394
K
G
F
Q
E
G
P
L
T
F
A
P
T
F
K
Chicken
Gallus gallus
XP_415287
1011
110631
A604
E
W
I
R
P
E
Q
A
V
V
K
Y
K
M
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_698057
784
85922
P410
A
I
E
N
D
K
L
P
L
L
W
E
K
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780987
442
50512
S68
D
P
W
T
E
V
I
S
S
I
V
C
P
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.8
78.9
87.5
N.A.
82.2
83.9
N.A.
56.2
42.2
N.A.
40.8
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
32.3
79.4
91.5
N.A.
86.7
88
N.A.
63.6
55.3
N.A.
51.1
N.A.
N.A.
N.A.
N.A.
29.3
P-Site Identity:
100
13.3
0
93.3
N.A.
100
100
N.A.
13.3
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
33.3
6.6
93.3
N.A.
100
100
N.A.
13.3
46.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
0
0
10
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
50
0
0
0
20
0
0
10
0
0
0
0
0
10
0
% D
% Glu:
10
0
10
0
20
20
0
0
0
0
0
10
10
0
0
% E
% Phe:
0
0
50
0
0
0
0
0
0
10
0
40
0
10
0
% F
% Gly:
0
10
0
0
0
10
0
0
0
0
0
0
0
50
10
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
10
0
0
40
10
0
0
10
0
0
0
0
0
% I
% Lys:
10
0
0
10
0
10
10
0
0
0
10
0
20
20
10
% K
% Leu:
10
0
0
10
0
0
50
10
50
20
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% M
% Asn:
0
40
0
10
0
0
0
0
0
0
10
0
0
0
10
% N
% Pro:
0
10
0
0
10
0
10
10
0
0
0
10
20
0
40
% P
% Gln:
0
0
10
50
0
0
10
0
10
40
40
0
30
0
10
% Q
% Arg:
0
10
0
10
0
0
10
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
60
10
10
0
0
0
0
10
% S
% Thr:
0
0
0
10
40
0
0
0
10
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
20
0
0
10
10
10
0
0
0
0
% V
% Trp:
0
10
10
0
10
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _